a Record control number 000298781000005

a ISSN 0001-527X

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QH325

b Item number .I5 2011

a Personal name Tandogan, B.

h Medium Electronic Document

a Title In vitro effects of compounds isolated from Sideritis brevibracteata on bovine kidney cortex glutathione reductase

c Statement of responsibility, etc B. Tandoğan, A. Güvenç, I. Çalış, N.N. Ulusu

c Date of publication, distribution, etc 2011.

b Name of publisher, distributor, etc Acta Bıochımıca Polonıca,

a Summary, etc Glutathione reductase (GR, E.C 1.6.4.2) is a flavoprotein that catalyzes NADPH-dependent reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH). The aim of this study was to investigate in vitro effects of phenolic compounds isolated from Sideritis brevibracteata on bovine kidney GR. The Sideritis species are widely found in nature and commonly used as medicinal plants. 7-O-glycosides of 8-OH-flavones (hypolaetin, isoscutellarein and 3'-hydroxy-4'-O-methylisoscutellarein) were isolated from aerial parts of Sideritis brevibracteata. These compounds inhibited bovine kidney cortex GR in a concentration-dependent manner. Kinetic characterization of the inhibition was also performed.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element glutathione reductase

a Topical term or geographic name as entry element Inhibition

a Topical term or geographic name as entry element kinetic

a Topical term or geographic name as entry element Sideritis brevibracteata

a Topical term or geographic name as entry element 8-hydroxyflavone glycosides

g Relationship information 2011, 58 4, p471-p475, 5p.

x International Standard Serial Number 0001527X

t Title Acta Bıochımıca Polonıca